Since 2003, when two winless teams play in Week 2 the underdog has gone 50-25-3 (67%) ATS

Week 2 matches:

Giants +1.5 at WAS
Packers +3.5 vs. IND
Browns +3 at JAC
Raiders +9.5 at BAL
Titans +3.5 vs. NYJ
Rams +1.5 at ARI

In the last 10 years, when two undefeated teams play in Week 2 the HOME team has gone 25-12 (68%) ATS

Week 2 matches:

Dolphins -2.5 vs. BUF
Cowboys -6.5 vs. NO
Lions -7 vs. TB
Vikings +6 vs. SF
Patriots +3 vs. SEA
Texans -7 vs. CHI

Since 2003, teams that lost in Week 1 and are underdogs in Week 2 have gone 104-80-5 (57%) ATS

Week 2 matches:

Giants +1.5
Packers +3.5
Browns +3
Panthers +6.5
Raiders +9.5
Titans +3.5
Rams +1.5
Broncos +3
Bengals +6
Falcons +6.5

NFL Week 2 total betting at BetMGM

Most bet OVERs

1. Giants-Commanders
2. Saints-Cowboys
3. 49ers-Vikings

Most bet UNDERs

1. Buccaneers-Lions
2. Colts-Packers
3. Falcons-Eagles

Popular (+60% of bets) NFL Week 2 plays at BetMGM

82% on Eagles -6.5
80% on Chargers -5.5
79% on Vikings +5.5
75% on Ravens -8
72% on Cowboys -6.5
72% on Commanders -1.5
70% on Patriots +3.5
70% on Texans -6.5

Saints @ Cowboys (-6.5)
Saints (1-0)
Last week, Saints outgained Carolina 379-193 in a 47-10 home win.
Saints were 7-13 on third down, +2 in turnovers.
Since 2018, New Orleans is 14-5-1 ATS as a road underdog.
QB Carr is 73-88 as an NFL starter.

Since 2010, Saints are 5-9 SU/2-12 ATS in road openers.
Last 3 years, New Orleans is 7-14-2 ATS coming off a win.
Under is 16-7 in their last 23 road games.

Cowboys (1-0)
LW, Dallas outgained Browns 265-230 in 33-17 road win.
Zimmer’s defense held Cleveland to 2.7 yards/pass attempt.
Last three years, Cowboys are 16-7 ATS as a home favorite.
Last three years, Dallas was 20-14 ATS coming off a win.

QB Prescott is 76-46 as an NFL starter.
Dallas is 5-2 ATS in last seven home openers.
Over is 31-17 in last 48 Dallas home games.

Teams split last six series games.
Saints are 2-2 SU/1-3 ATS in last four visits to Dallas.
Last four meetings stayed under the total.

Buccaneers @ Lions (-7.5)
Buccaneers (1-0)
Mayfield averaged 9.0 yards/pass attempt in LW’s 37-20 win vs Washington
Bucs were 9-13 on third down, Commanders 2-8.
Under Bowles, Tampa Bay is 7-3 ATS as a road underdog.
Last six years, Tampa Bay is 4-2 SU/ATS in road openers.

QB Mayfield is 43-48 as an NFL starter, 11-9 with Buccaneers.
Over is 10-6 in their last 16 road openers.
Last three years, under is 16-9 in Tampa Bay road games.

Lions (1-0)
LW, Lions tied game late, won home opener 26-20 in overtime.
Under Campbell, Lions are 10-4 ATS as a home favorite.
Last two years, Detroit is 13-6 ATS coming off a win.

Lions were 6-13 on 3rd down LW, but allowed 304 PY.
Goff is 27-24-1 as Detroit’s QB (was 44-30 with Rams)
Over is 12-6 in their last 18 home games.

Detroit (-6) beat Tampa Bay 31-23 in LY’s playoffs.
Lions won six of last nine series games.
Buccaneers are 4-2 SU/ATS in last six visits to Detroit.

Browns @ Jaguars (-3)
Browns (0-1)
Cleveland gained only 230 TY in LW’s 33-17 home loss to Dallas.
Browns were 2-15 on 3rd down vs Dallas, 3-5 on 4th down.
Last three years, Cleveland is 6-10-1 ATS as road underdog.
QB Watson is 37-32 as an NFL starter, 8-5 with Browns.

Cleveland is 10-3-1 ATS in last 14 games coming off a loss.
Cleveland is 2-4 SU/4-2 ATS in its last six road openers.
Over is 3-0 in Browns’ last three road openers.

Jaguars (0-1)
Jaguars were outgained 400-267 in LW’s 20-17 loss at Miami.
LY, Jaguars were 4-2 ATS as home favorite (5-14 from 2016-22).
QB Lawrence is 21-32 as an NFL starter.
Jaguars are 3-9 ATS in last 12 home openers (3-3 ATS in last six).

Jacksonville’s last three home openers stayed under the total.
Jaguars are 19-18 SU under Pederson (15-50 previous four years)
Under Pederson, Jaguars are 8-7 ATS in games with spread of 3 or fewer points.

Browns won last two meetings, 31-27/27-25.
Browns are 1-2 SU/0-3 ATS in last three visits to Jacksonville.
Over is 5-3 in last eight series games.

49ers (-6.5) @ Vikings
49ers (1-0)
Short week/long travel for 49ers after their Monday nite game.
49ers outgained Jets 401-266 in Monday’s 32-19 win.
Since 2020, San Francisco is 15-10-1 ATS as a road favorite.
Since 2019, 49ers are 27-22-1 ATS coming off a win.

QB Purdy is 22-5 as an NFL starter.
Since 2008, 49ers are 11-7 ATS in road openers.
Under is 5-2 in their last seven road openers.

Vikings (1-0)
Minnesota outgained Giants 312-220 in LW’s 28-6 road win.
Last week was first time in 8 years that Vikings won their road opener.
Under O’Connell, Vikings are 2-4 ATS as a home underdog.
Minnesota is 7-2 ATS in last nine home openers.

QB Darnold is 22-35 as an NFL starter.
Vikings 5-1-1 ATS LY in games coming off a win.
Minnesota is one of 7 teams with same HC, coordinators as LY.
Under is 9-1 in their last ten home openers.

Home team won last seven series games.
49ers are 0-4 SU/1-3 ATS in last four visits to Minnesota.
Under is 5-1 in last six meetings.

Chargers (-6.5) @ Panthers
Chargers (1-0)
Chargers ran for 176 yards in LW’s 22-10 home win over Las Vegas.
Last two years, Bolts were 5-3-2 ATS as a road favorite.
Since 2019, Bolts are 13-16-5 ATS coming off a win.
QB Herbert is 31-33 as an NFL starter.

Last 8 years, Chargers are 5-2-1 ATS in their road opener.
Since 2020, Chargers are 9-7-3 ATS vs AFC opponents.
Harbaugh was 49-22-1 as 49ers’ coach (2011-14).
Under is 4-1 in their last five road openers.

Panthers (0-1)
LW, Panthers gained only 193 TY in ugly 47-10 loss in New Orleans
Saints outrushed Carolina, 180-58.
Last three games, Carolina was outscored by a combined 82-10.
Since 2019, Carolina is 10-13-2 ATS as home underdog.

2nd year QB Young is 2-15 as an NFL starter.
Last 5 years, Carolina is 1-3-1ATS in home openers.
Since 1996, under is 18-9-1 in Panthers’ home openers.
Last three years, Carolina is 5-10 ATS vs AFC opponents.

Carolina won/covered last four series games.
Chargers are 1-2 SU/2-1 ATS in last three visits to Charlotte.
Under is 4-1 in last five meetings.

Raiders @ Ravens (-9)
Raiders (0-1)
Raiders were minus-3 in turnovers, gained only 296 yards in LW’s 22-10 loss.
Raiders are 13-18-1 ATS in game following their last 32 losses.
QB Minshew is 15-23 as an NFL starter; Raiders are his 4th team.
Since 2019, Las Vegas is 19-12 ATS as a road underdog.

Raiders are 8-2-1 ATS in last 11 road openers.
Since start of 2020, Raiders are minus-32 in turnovers in 68 games.
Under is 17-9 in their last 26 road games, 5-2 in last seven road openers.

Ravens (1-0)
Ravens outgained KC 452-353 but lost opener 27-20 at Arrowhead.
QB Jackson threw for 273 yards, ran for 185 more,
Derrick Henry ran ball only 13 times, for 46 yards,
Since 2021, Ravens are 9-13 ATS as a home favorite.
QB Jackson is 60-24 as an NFL starter.

Since 2005, Ravens are 12-6 ATS in their home opener.
Last two years, under is 11-6 in Baltimore’s home games.
Ravens have a first-time defensive coordinator.
Last four years, Baltimore is 12-10 ATS coming off a loss.

Teams split their last six meetings.
Teams haven’t met since 2021.
Raiders are 1-4 SU/ATS in last five visits to Baltimore.
Last six series games went over the total.

Seahawks (-3.5) @ Patriots
Seahawks (1-0)
Seattle outgained Denver 304-231 in LW’s 26-20 home win.
Last four years, Seahawks are 5-8-1 ATS as road favorites.
Since 2019, Seattle is 4-1 SU/ATS in road openers.
Seattle is 11-7-2 ATS last 20 games vs AFC opponents.

QB Smith is 31-37 as an NFL starter, 19-18 with Seattle.
Under is 10-3 in their last 13 road openers.
Seahawks are 11-19-2 in last 32 games coming off a win.
Under is 14-9-1 in their last 24 road games.

Patriots (1-0)
Patriots held Bengals to 224 TY in LW’s 16-10 upset win.
New England ran ball for 170 yards, threw for only 120
Last two years, New England is 1-8 ATS as a home underdog.

Last three years, Patriots are 0-3 SU/ATS in home openers.
New England is 7-12 ATS in last 19 games vs NFC teams.
Patriots QB Brissett is 19-30 as an NFL starter.

Seattle won/covered last three series games.
Seahawks split their last two visits to Foxboro.
Last five series games went over the total.

Colts (-3) @ Packers
Colts (0-1)
LW, Colts gave up 213 rushing yards in their 29-27 home loss.
Indy completed only 9-19 passes, averaged 20+ yards/reception.
Last nine years, Colts are 2-6-1 ATS in road openers.
Last four years, Colts are 8-4 ATS as road favorites.

Colts are 22-12-1 ATS in last 35 games on natural grass
Indy is 17-12-1 ATS in last 30 games coming off a loss.
2nd-year QB Richardson is 2-3 as an NFL starter.
Colts are one of 7 teams with same HC, coordinators as LY.

Packers (0-1)
QB Love isn’t expected to play; Malik Willis would replace him.
Willis was 1-2 as a starter for Tennessee in 2022.
Green Bay is 19-9 ATS in last 28 games as an underdog.
Last nine years, Packers are 7-2 ATS in home openers.
Since 2018, Green Bay is 15-12-1 ATS vs AFC opponents.

LW, Packers outgained Eagles 414-410 in 34-29 loss.
QB Willis is 1-2 as an NFL starter; Love is 10-11.
Under is 5-2 in Green Bay’s last seven home openers.
Former Boston College HC Hafley is Green Bay’s new DC.

Colts won last three series games, by 3-5-3 points.
Teams split their last two meetings at Lambeau Field.
Last five series games went over the total.

Jets (-4.5) @ Titans
Jets (0-1)
Short week, more travel for Jets after their Monday night loss.
Jets were outgained 401-266 in Monday night’s loss.
49ers outrushed them 180-68 Monday night.
Since 2017, Jets are 1-6-1 ATS as a road favorite.

Since 2018, Jets are 26-38 ATS coming off a loss.
Rodgers is 159-86-1 as an NFL starter.
Under is 18-13 in their last 31 road games.

Titans (0-1)
Titans lost 24-17 in Chicago LW, without giving up an offensive TD.
Bears blocked a punt for a TD, also had a pick-6.
Tennessee is 9-4-1 ATS in last 14 games as a home underdog.
Since 2016, Titans are 33-22-3 ATS coming off a loss.

Tennessee is 2-8-1 ATS in its last 11 home openers.
Under is 5-2 in their last seven home openers.
QB Levis is 3-7 as an NFL starter.
Titans have an all-new coaching staff.

Jets won three of last four games with Tennessee.
Gang Green is 2-4 SU/4-2 ATS in last six visits to Nashville.
Over is 5-3 in last eight series games.

Giants @ Commanders (-1.5)
Giants (0-1)
Giants were outgained 312-240 in LW’s 28-6 home loss.
Last four years, Giants are 2-2 SU/3-1 ATS in road openers.
Those four games were decided by total of 10 points.
Since 2018, Giants are 28-16 ATS as road underdogs.

Under Daboll, Giants are 12-5 ATS coming off a loss.
Under Daboll, Giants are 5-1 ATS in NFC East road games.
QB Jones is 23-38-1 as an NFL starter.
Under Daboll, Giants are 5-5-1 ATS in games with spread of 3 or fewer points.
New defensive coordinator for Big Blue this season.

Commanders (0-1)
Bucs outgained Washington 392-299 in LW’s 37-20 Tampa Bay win.
Commanders were 2-8 on third down, Bucs were 9-13.
Rookie QB Daniels was 17-24/184 passing in his first NFL start.
Washington is 4-10 ATS in last 14 games as a home favorite.

Commanders are 2-6-1 ATS in last nine NFC East home games.
Last eight years, Washington is 3-5 SU/2-6 ATS in home openers.
Washington is 14-9-2 ATS in last 25 games with spread of 3 or fewer points.
Over is 8-5 in their last 13 home openers.
Commanders are 11-18-1 ATS in last 30 games coming off a loss.

Giants are 7-2-1 SU in last ten series games.
Big Blue covered its last six visits here.
Under is 7-2 in last nine meetings.

Rams @ Cardinals (-1.5)
Rams (0-1)
Rams have pretty severe injury problems on offensive line.
Rams threw for 304 yards LY, but lost 26-20 in OT at Detroit.
Under McVay, Rams are 23-16-1 ATS coming off a loss.
Last two years, LA is 4-7-2 ATS as a road underdog.

Under is 10-6-1 in Rams’ last 17 road games.
LA is 7-2 ATS in its last nine NFC West road games.
WR Kupp caught 14 passes for 110 yards and a TD last week.
QB Stafford is 28-19 as Rams’ QB (was 74-93-1 with Detroit).

Cardinals (0-1)
Arizona lost 34-28 at Buffalo LW, after leading 17-3.
Cardinals are 5-14-1 ATS in last 20 games as home favorites.
Last five years, Arizona is 4-11 ATS in NFC West home games.
Cardinals are 9-8 ATS in last 17 games with spread of 3 or fewer points.

QB Murray is 28-38-1 SU as an NFL starter.
Cardinals are 3-5 ATS in last eight home openers.
Over is 4-1 in their last five home openers.
Arizona is one of 7 teams with same HC, coordinators as LY.

Rams won three in row, 14 of last 16 series games.
Rams are 9-0 ATS in last nine visits to Arizona.
Over is 4-2 in last six meetings.

Bengals @ Chiefs (-5.5)
Bengals (0-1)
Bengals were held to 224 yards in LW’s 16-10 home loss.
Bengals were 4-11 on 3rd down, averaged 4.8 yards/pass attempt.
Bengals lost their last five road openers (0-3 ATS last three).
Cincinnati is 6-3-1 ATS in last 10 games as a road underdog.

QB Burrow is 34-25-1 as an NFL starter.
Last four years, Cincinnati is 17-10-1 ATS coming off a loss.
WR Chase, who is in a contract dispute, caught six balls for 62 yards LW
Bengals ran only 48 plays in Sunday’s loss; New England ran 64.

Chiefs (1-0)
Chiefs outgained Ravens 452-353 in LW’s 27-20 home win,
Kansas City played on Thursday LW, had extra time to prep for this.
Chiefs are 19-28-1 in last 48 games coming off a win.
Last 4+ years, under is 21-12-1 in games at Arrowhead.

Last 4+ years, KC is 15-17 ATS as a home favorite.
QB Mahomes is 90-25 as an NFL starter.
WR Rice caught seven passes for 103 yards LW.
In Week 1, individual team totals were 16-13-1 to the over.

Teams split their last six meetings.
Bengals are 3-5 ATS in last eight visits to Arrowhead.
Under is 8-2 in last ten series games.

Steelers (-3) @ Broncos
Steelers (1-0)
Steelers held Atlanta to 226 yards in LW’s 18-10 road win.
Pittsburgh was +3 in turnovers LW, converted 8-17 third down plays.
Since 2020, Pittsburgh is 4-3 as a road favorite.
Steelers are 17-9-1 ATS in last 27 games with spread of 3 or fewer points.

QB Fields is 11-28 as an NFL starter (1-0 with Steelers).
Pittsburgh is 9-6-1 in its last 16 games coming off a win.
Under is 8-2 in their last ten road games.
Russell Wilson was Denver’s QB the last two years; he won’t play here, but he is on the Steelers’ bench.

Broncos (0-1)
Rookie QB Nix averaged 3.3 yards/pass attempt in his first NFL start.
Denver is 6-1 ATS in its last seven games as a home underdog.
In his career, Payton is 51-34-2 ATS as an underdog.
Denver was held to 231 TY LW; they were 5-18 on third down.

Since 2000, Denver is 20-4 SU/15-9 ATS in home openers.
Denver’s last five home openers stayed under the total.
Broncos are 9-17-1 ATS in last 27 games with spread of 3 or fewer points.
Broncos are 13-15-1 ATS in last 29 games coming off a loss.

Home team won last six series games.
Steelers are 1-4 SU/ATS in last five visits to Denver.
Over is 8-2 in last ten meetings.

Bears @ Texans (-6.5)
Bears (1-0)
Bears won 24-17 LW, despite not scoring an offensive TD.
Chicago was outgained 244-148; blocked punt for TD, had a pick-6.
Bears are 9-15-1 ATS in last 25 games as a road underdog.
Chicago is 5-11 ATS in last 16 games coming off a win.

Bears are 4-2 SU/3-3 ATS in last six road openers.
Under is 6-1 in their last seven road openers.
Under Eberflus, Bears are 5-5-1 ATS vs AFC opponents.
Bears have a 3rd-year HC but have two new coordinators TY.

Texans (1-0)
Texans ran for 213 yards, held off Colts 29-27 at Indy last week.
Houston was 10-7 LY, its first winning year since 2019.
Since 2019, Texans are 4-11 ATS as a home favorite.
Houston is 4-7 ATS in last 11 games coming off a win.

Last 7 years, Texans are 2-5 ATS in home openers.
Over is 3-1 in last four home openers.
2nd-year QB Stroud is 11-7 as an NFL starter.
Houston is one of 7 teams with same HC, coordinators as LY.

Home team won four of last five series games.
Bears lost 23-14/31-24 in their two visits to Houston.
Under is 4-2 in series games.

Los Angeles Chargers (-5.5; 39) at Carolina Panthers
Sunday, 1:00 p.m. ET (CBS)

Last week could not have gone any worse for Dave Canales, who is making his debut as Carolina head coach. The Panthers allowed the Saints to score on their first nine drives, totaling 47 points. Bryce Young still has a long way to go, only going 13-for-30 for 161 yards with two interceptions and a QBR of 12.3, plus he was sacked four times. On defense, Pro Bowl DT Derrick Brown is now out for the season with a knee injury. The Panthers’ situation cannot get any worse through Week 1, but it is just Week 1.

Jim Harbaugh won in his debut as Chargers head coach with a 22-10 victory over the Raiders, but the game was closer than the final score indicated. The Raiders went -3 in turnovers, and Antonio Pierce cost his team any chance at victory when he punted on 4th-and-1 at the Chargers 43 with just seven minutes left to play. Nevertheless, the Chargers looked relatively pedestrian on offense until the 61-yard run by J.K. Dobbins on the final drive that sealed the game.

This is a “hold your nose” and anything else you can hold onto play. Over the last 20 years, teams that lose by 35 or more and underdogs of 4 or more the following week are 50-18-2 ATS. The betting public could drive this back to 6, where I grabbed it, but these are the spots you have to be willing to back in Week 2 against the market overreactions.

NFL Week 2 Best Bet: Carolina Panthers +5.5