Personaly I like to go against a star QB in the first game back. The timing just never seems to be there and the line is always off because the public thinks the QB coming back will turn the team around. That being said Carolina is the better team with a dominant run game against the worst ranked rush defense. This will be the key to the game IMO.
Miller, what you posted about the running game on both sides together with the info on Vick's timing maybe being rusty, would lead me to think Carolina and the under. Maybe a tease with added points is the way to go? Canbet has Car. -1 with the over/under at 42.